Linking Cell Death and Autophagy Pathways in the Heart


题目:Linking Cell Death and Autophagy Pathways in the Heart.


Richard N. Kitsis, M.D.

Professor of Medicine and Cell Biology

The Dr. Gerald and Myra Dorros Chair in Cardiovascular Disease

Director, Wilf Family Cardiovascular Research Institute

Albert Einstein College of Medicine

New York City, USA



联系人:肖瑞平 北京大学分子医学研究所

The Kitsis lab has discovered unexpected connections between autophagy and mitochondrial function.  At the disease level, these connections appear to function in the final common pathway for heart failure.  At the fundamental biology level, they may be relevant to how eukaryotic cells evolved to “govern” mitochondria when these organelles transitioned from bacteria-like to  endosymbionts.