两院院士

程京

  • 教授(Professor Jing Cheng)

  清华大学医学院长江学者计划特聘教授,生物芯片北京国家工程研究中心主任,中组部千人计划入选者,中国工程院院士、国际欧亚科学院院士。1992年在英国史查克莱大学纯粹及应用化学系获司法生物学博士学位。从事基础医学和临床医学相关生物技术研究,在生物芯片的研究中有重要建树和创新。主持研制了生物芯片类产品及配套仪器共60余项,获国内外发明专利共208项,获医疗器械注册证51项,欧盟CE认证证书31个,获批临床诊断类生物芯片行业标准7项、国家标准5项。主编中英文著作各4部,发表SCI论文130余篇,SCI他引4600余次。获国家杰出青年科学基金、国家技术发明奖二等奖、何梁何利科学与技术创新奖、中国工程院光华工程科技奖和中国科学年度新闻人物等奖励和荣誉。

主要研究领域:

  主要从事分子检测、细胞检测和大健康相关研究。

代表性论文:

  1.Xie X., Liu R., Xu Y., Wang L., Lan Z., Chen W., Liu H., Lu Y., Cheng J. *. In vitro hyperthermia studied in a continuous manner using electric impedance sensing. RSC Advances, 2015, 5:62007-62016.

  2.Xu Y., Xie X., Duan Y., Wang L., Cheng Z., Cheng J. *. Review of impedance measurements of whole cells. Biosens Bioelectron, 2015, 77:824-836.

  3.Lv Y., Zeng L., Zhang G., Xu Y., Lu,Y., Mitchelson K., Cheng J. *, Xing W. Systematic Dielectrophoretic Analysis Of The Ara-C-Induced Nb4 Cell Apoptosis Combined With Gene Expression Profiling. International Journal Of Nanomedicine, 2013, 8: 2333-2350.

  4.Guo, H., Liu, H., Mitchelson, K., Rao, H., Luo, M., Xie, L., Sun, Y., Zhang, L., Lu, Ying., Liu, R., Ren, A., Liu, S., Zhou, S., Zhu, J., Zhou, Y., Huang, A., Wei, L., Guo, Y. and Cheng, J. * . MicroRNAs-372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B . Hepetology, 2011, 54 (3): 808–819.

  5.Wang, L., Wang, L., Yin, H., Xing, W., Yu, Z., Guo, M. and Cheng, J.*. Real-time, label-free monitoring of the cell cycle with a cellular impedance sensing chip. Biosensors and Bioelectronics, 2010, 25(5): 990-995.

  6.Li, C., Pan, Q., Guo, Y., Li, Y., Gao, H., Zhang, D., Hu, H., Xing, W., Mitchelson, K., Xia, K., Dai, P. and Cheng, J.*. Construction of a multiplex allele-specific PCR-based universal array(ASPUA) and its application to hearing loss screening . Human Mutation , 2008, 29(2): 306-314.

  7.Du, H., Wu, M., Yang, W., Yuan, G., Sun, Y., Lu, Y., Zhao, S., Du, Q., Wang, F., Yan, S., Pan, M., Lu, Y., Wang, S. and Cheng, J. *. Development of miniaturized competitive immunoassays on a protein chip as a screening tool for drugs. Clinical Chemistry, 2005, 51(2): 368-375.

  8. Cheng, J. * ,Sheldon, E.L., Wu, L., Uribe, A., Gerrue, L.O., Heller, M.J. and O¢Connell, J.P. Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricatedbioelectronic chips. Nature Biotechnology, 1998, 16(6): 541-546.